The gene encoding PDX1 (pancreatic duodenum homeobox 1), the main transcription factor regulating the glucose-dependent transactivation of the insulin promoter in pancreatic β-cells, clusters with two closely related homeobox genes (Gsh1 and Cdx2/3), all of them belonging to the ParaHox gene family.The ParaHox gene evolutionary history in the
Group A Streptococcus (GAS) is a human specific pathogen capable of causing Saccharomyces Boulardii both mild infections and severe invasive disease.We and others have shown that GAS is able to form biofilms during infection.That is to say, they form a three-dimensional, surface attached structure consisting of bacteria and a multi-component extrac
Human metapneumovirus (HMPV) is an important cause of upper and lower respiratory tract disease in individuals of all ages.It is estimated that most individuals will be infected by HMPV by the OREGANUM PLUS 1:1 age of five years old.Despite this burden of disease, there remain caveats in our knowledge of global genetic diversity due to a lack of HM